Moisture loss is one of the leading causes of skin wrinkles and results in a breakdown of collagen. On average, our skin will lose about 0.5 milligrams per centimeter of skin per hour during the day, and twice that amount or more is lost during the night time. Over eight hours of sleep, that is a loss of about five teaspoons of water! The amount of water passing through the skin is critical since too much water will macerate the skin and too little will leave the skin hard and dry.